G2Herman: My bet is that just as with ayahuasca or phenethylamines, it is JUST AS MUCH mindset/emotional-physical vibratory state as it is any nauseating compounds, if not more so the former...
What would help us further with this would be to take a real solid look at the body of PURE LA-111 reports, and see if nausea is a significant factor in them...if it is, then you have your answer..
and by the way, i don't know if chanoclavine is a cyano-compound...i remember reading that it was an lysergoid/ergoloid compound, but i may be wrong...i'll try to get a link when the valerian isn't kicking in

goodnight!