Chem Pharm Bull (Tokyo). 2001 Jul;49(7):927-9. Related Articles, Links

Diastereomeric diterpenes from Coleus blumei.

Ragas CY, Templora VF, Rideout JA.

Chemistry Department, De La Salle University, Manila, Philippines.

The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (ID, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans.